PowerPlex® Y23 System
5-Dye STR Multiplex for Amplification of 23 Y-STR Loci
- High sensitivity in the presence of female DNA
- High tolerance for inhibitors
- Rapid-cycling protocols reduce amplification time by half
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Catalog Number: DC2305
Catalog Number: DC2320
Catalog Number: DM6571
Amplify 23 Y-STR Loci in a Single Reaction
The PowerPlex® Y23 System is a 23-loci, 5-color Y-STR multiplex designed for genotyping forensic casework samples, database samples and paternity samples. Higher power of discrimination from 23 loci results in fewer false-positive matches and more meaningful STR analysis. A single kit for both casework and databasing simplifies your workflow.
The PowerPlex® Y23 System allows co-amplification and four-color detection of 23 male-specific STR loci: DYS576, DYS389I/II, DYS448, DYS19, DYS391, DYS481, DYS549, DYS533, DYS438 (penta), DYS437, DYS570, DYS635, DYS390, DYS439, DYS392, DYS643 (penta), DYS393, DYS458, DYS385a/b, DYS456 and Y-GATA-H4.
For laboratories that store their plates up to 48 hours prior to injection, we recommend the use of the optional Stabilizer Reagent (Cat.# DM6571), sold separately.
New!
Learn how to interpret results from Y-STR DNA typing using the Y-Chromosome Haplotype Reference Database (YHRD), a free resource.
Promega forensic products are manufactured in alignment with the ISO 18385 standard. This standard ensures minimal risk of human DNA contamination for products used to collect, store and analyze biological materials for forensic purposes. Learn more.
Amplify Only Male DNA
The PowerPlex® Y23 System can successfully amplify trace amounts of male DNA, even in the presence of overabundant amounts of female DNA.
Obtain Full Profiles from the Most Challenging Samples
The PowerPlex® Y23 System is a robust multiplex that is tolerant of many amplification inhibitors, including hematin, tannic acid and humic acid. The robust performance of the kit results in more interpretable data and less need for re-amplification of inhibitor-laden samples.
Streamline Workflows with Direct Amplification
The PowerPlex® Y23 System also is compatible with direct amplification, enabling streamlined Y-STR databasing efforts. Amplification can be successfully performed with sample types such as FTA® card punches as well as pretreated swabs, Bode Buccal DNA Collector™ punches or S&S 903 punches. Faster cycling conditions cut amplification time almost in half. Moreover, reduced sample-processing time and faster cycling conditions provide a significant time savings in every run.
Buccal Sample on FTA® Card
Swab Sample with SwabSolutionâ„¢ Reagent
Buccal Sample with PunchSolutionâ„¢ Reagent
Rapid Processing Solutions for PowerPlex® Systems
The 5X AmpSolution™ Reagent, SwabSolution™ Kit and PunchSolution™ Kit allow fast and simple processing of swabs and punches for analysis with various PowerPlex® Systems, including the PowerPlex® Fusion, 21, 18D, 16 HS, ESX, ESI, CS7 and Y23 Systems. These products are intended for preparation of single-source reference, database and paternity samples where sample purification is unnecessary.
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Protocols
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Specifications
Catalog Number:
What's in the box?
| Item | Part # | Size | Concentration | Available Separately |
|---|---|---|---|---|
|
2800M Control DNA |
DD710A | 1 × 25μl | 10ng/μl | View Product |
| PowerPlex® Y23 5X Master Mix | DP108A | 1 × 250μl | ||
|
Water, Amplification Grade |
DW099A | 1 × 1,250μl | View Product | |
| PowerPlex® Y23 Allelic Ladder Mix | DG248B | 1 × 25μl | ||
WEN Internal Lane Standard 500 Y23 |
DG520A | 1 × 200μl | View Product | |
| PowerPlex® Y23 10X Primer Pair Mix | DK209B | 1 × 125μl |
SDS
Search for SDSCertificate of Analysis
Use Restrictions
Not For Medical Diagnostic Use.Storage Conditions
U.S. Pat. No. 9,139,868, European Pat. No. 2972229, Japanese Pat. No. 6367307 and other patents pending.
TMR-ET, CXR-ET and WEN dyes are proprietary.
What's in the box?
| Item | Part # | Size | Concentration | Available Separately |
|---|---|---|---|---|
|
2800M Control DNA |
DD710A | 1 × 25μl | 10ng/μl | View Product |
|
Water, Amplification Grade |
DW099A | 5 × 1,250μl | View Product | |
| PowerPlex® Y23 Allelic Ladder Mix | DG248B | 4 × 25μl | ||
WEN Internal Lane Standard 500 Y23 |
DG520A | 1 × 200μl | View Product | |
| PowerPlex® Y23 10X Primer Pair Mix | DK209B | 4 × 125μl | ||
| PowerPlex® Y23 5X Master Mix | DP108A | 4 × 250μl |
SDS
Search for SDSCertificate of Analysis
Use Restrictions
Not For Medical Diagnostic Use.Storage Conditions
U.S. Pat. No. 9,139,868, European Pat. No. 2972229, Japanese Pat. No. 6367307 and other patents pending.
TMR-ET, CXR-ET and WEN dyes are proprietary.
What's in the box?
| Item | Part # | Size |
|---|---|---|
Stabilizer Reagent |
DM657A | 1 × 0.25ml |
SDS
Search for SDSCertificate of Analysis
Use Restrictions
For Research Use Only. Not for Use in Diagnostic Procedures.Storage Conditions
Resources
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Software and Firmware
Other Resources
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Frequently Used With
PowerPlex® Matrix Standards
DNA fragments labeled with fluorescent dyes for use with the PowerPlex® Systems.
DG4800, DG4850, DG4900, DG5010
PowerQuant® System
5-color, 4-target probe-based qPCR assay.
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2800M Control DNA
For human STR analysis.
DD7101, DD7251
5X AmpSolutionâ„¢ Reagent, PunchSolutionâ„¢ Kit and SwabSolutionâ„¢ Kit
Rapid, simple preparation methods for swabs and punches for direct amplification using PowerPlex® STR Systems.
DM1231, DC9271, DC8271
